| Network parameters |
Average value |
Name of molecules |
| In-degree |
1.97 |
NOTCH1, NOTCH2, NOTCH3, NOTCH4, GAMMA_SECRETASE, NICD1, NICD2, NICD3, NICD4, NOTCH1_PRE, NOTCH2_PRE, NOTCH3_PRE, NOTCH4_PRE, NUC_NICD1, NUC_NICD2, NUC_NICD3, NUC_NICD4, CSL, COA, SMRT, COR, HDAC, YY1, STAT3 |
| Out-degree |
1.97 |
JAG1, JAG2, DLL1, DLL4, DLL3, TACE, GAMMA_SECRETASE, DVL, POGLUT1, O_GLUCOSE, POFUT_1, O_FUCOSE, XYLE, XYL, GASE, GALACTOSE, FRINGE, NGA, GSK_3BETA, P53_P, NUC_NICD1, NUC_NICD2, NUC_NICD3, NUC_NICD4, CSL, DTX1, FBW7, SKIP, CDK8, HIF1A, HES1, NRARP |
| Total-degree |
3.94 |
NOTCH1, NOTCH2, NOTCH3, NOTCH4, GAMMA_SECRETASE, NICD1, NICD2, NICD3, NICD4, NOTCH1_PRE, NOTCH2_PRE, POGLUT1, O_GLUCOSE, NOTCH3_PRE, NOTCH4_PRE, POFUT_1, O_FUCOSE, XYLE, XYL, GASE, GALACTOSE, FRINGE, NGA, P53_P, NUC_NICD1, NUC_NICD2, NUC_NICD3, NUC_NICD4, CSL, COA, SMRT, COR, HDAC, CDK8, YY1, HIF1A, NRARP |
| Eigenvector centrality |
0.20 |
NICD1, NICD2, NICD3, NICD4, NOTCH1_PRE, NOTCH2_PRE, NOTCH3_PRE, NOTCH4_PRE, NUC_NICD1, COA, HAT, SMRT, COR, HDAC, YY1, HES1, STAT3, HES5, JAK2, HEY1, HEY2, MAG, NRARP, NFKB, MYOD, GATA3, CD44, P21, KLF5, PTCRA, REL_B, C_REL, P50, P65, SOX9, BCL2, IAP, FLIP, CCND1, CCND3, MKP_1, HEYL, HES7 |
| Closeness centrality |
0.002 |
JAG1, NOTCH1, JAG2, DLL1, DLL4, DLL3, NOTCH2, NOTCH3, NOTCH4, MAGP1, MAGP2, TACE, NOV, CNTN1, PRESENILIN1, GAMMA_SECRETASE, APH1, NICASTRIN, PEN2, NEXT1, NEXT2, NEXT3, NEXT4, NICD1, NICD2, NICD3, NICD4, DVL, WDR12, GSK_3BETA, JIP1, RAS, P53, P53_P, NUC_NICD1, NUC_NICD2, NUC_NICD3, NUC_NICD4, SMAD3, CSL, DTX1, FBW7, EP300, COA, SKIP, HAT, MAML, SMRT, COR, SAP30, HDAC, CIR, SIN3A, CDK8, STAT3_P, NUC_STAT3, HIF1A, HES1, STAT3, HES5, JAK2, NRARP |
| Betweenness centrality |
107.94 |
NOTCH1, NOTCH2, GAMMA_SECRETASE, NEXT1, NEXT2, NEXT3, NEXT4, NICD1, NICD2, NICD3, NICD4, NUC_NICD1, NUC_NICD2, NUC_NICD3, NUC_NICD4, CSL, COA, COR, STAT3_P, NUC_STAT3, HIF1A, HES1, STAT3, HES5, NRARP, PTEN |
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