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Figure 13: Interacting Proteins of the C-terminus of GPCRs. Diagram representing the three regions of the C-terminal domain known to interact with intracellular proteins. The first region is called the helix-8 and is an α-helix that terminates with palmitoylated cysteine residues. The second includes the PDZ domain and is located at the very end of the C-terminal domain. And the region in between that is known as ‘binding sites with GPCR interacting proteins’.
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