| |
Control |
MDT |
| Zero |
3-month |
6-month |
12-month |
Zero |
3-month |
6-month |
12-month |
| AST (IU/ml) |
M |
35.2 ± 10.3 |
37.1 ± 11.2 |
35.3 ± 10.6 |
35.1 ± 10.4 |
35.5 ± 10.7 |
40.1 ± 12.1* |
41.9 ± 12.9* |
44.0 ± 13.6* |
| F |
25.8 ± 7.4 |
25.0 ± 7.3 |
23.5 ± 7.4 |
23.8 ± 7.3 |
23.7 ± 7.1 |
26.7 ± 8.4* |
28.2 ± 8.6* |
29.3 ± 8.8* |
| ALT (IU/ml) |
M |
43.7 ± 16.4 |
51.4 ± 13.8 |
48.1 ± 12.0 |
47.9 ± 12.2 |
47.5 ± 12.0 |
55.6 ± 14.0* |
61.2 ± 15.4* |
63.5 ± 16.2* |
| F |
25.8 ± 7.4 |
24.9 ± 7.3 |
23.5 ± 7.4 |
23.8 ± 7.3 |
23.7 ± 7.1 |
26.7 ± 8.4* |
28.2 ± 8.6* |
29.3 ± 8.8* |
| Total billirubin (mg%) |
M |
0.81 ± 0.23 |
0.84 ± 0.22 |
0.8 ± 0.20 |
0.81 ± 0.22 |
0.81 ± 0.21 |
0.90 ± 0.23 |
0.96 ± 0.26* |
1.00 ± 0.27* |
| F |
0.85 ± 0.21 |
0.93 ± 0.20 |
0.87 ± 0.19 |
0.88 ± 0.19 |
0.88 ± 0.18 |
0.99 ± 0.21* |
1.05 ± 0.23* |
1.09 ± 0.23* |
| Creatinine (mg%) |
M |
1.00 ± 0.18 |
1.07 ± 0.18 |
1.02 ± 0.18 |
1.02 ± 0.18 |
1.02 ± 0.17 |
1.19 ± 0.2* |
1.29 ± 0.21* |
1.07 ± 0.18* |
| F |
0.86 ± 0.13 |
0.91 ± 0.17 |
0.85 ± 0.16 |
0.87 ± 0.16 |
0.85 ± 0.15 |
0.99 ± 0.18* |
1.08 ± 0.21* |
1.13 ± 0.21* |
*Significantly different from corresponding control group (p<0.05). |
