Reproduced from reference [1] by kind permission of Elsevier Press.
Glycol=Glycolysis; E.R=Endoplasmic Reticulum Extracts from a video sequence in reference [1]. In the first frame top left the shape is seen to be bounded by an irregular circumference. As the shape enlarges, this circumference appears to be made of similar out-pouches. Each of these pouches then starts to replicate its own shape. Each new outpouching then generates further ones all linked by similar extensions and enlargements. This can be viewed as representing an entropic map. As energy is dissipated in an original focus, it radiates into a similar “shape”. Molecules entrapped within one shape or possessing appropriate attributes can enter another when conditions are thermodynamically permissive and their interaction then creates an extension of the entropy map, for example, the white arrow. Because of the fractal organisation, widely different foci can function and many signalling systems can co-exist and meet, but also be integrated into the whole. The entire map is highly fluid. The links between foci can be thought of as entropic “corridors” between sites and the spaces within the shapes as nano-domains in Figure 2.
