| Groups |
Urea (mg/dl) |
Uric acid (mg/dl) |
Serum creatinine (mg/dl) |
Serum total protein (g/dl) |
Urine total protein (mg/dl) |
Urine albumin (mg/dl) |
Serum glucose levels (mg/dl) |
| 1st day |
15th day |
Nondiabetic control
(5% DMSO in 0.9% NaCl, 5 ml/kg) |
24.38±2.15 |
2.92±0.15 |
0.73±0.06 |
7.14±0.23 |
14.68±0.89 |
2.30±0.13
|
85.64±1.99 |
86.60±1.91 |
| STZ‑induced diabetic control(5% DMSO in 0.9% NaCl, 5 ml/kg)) |
61.73±1.72a,** |
3.99±2.15 a,** |
1.96±0.13 a,** |
3.26±0.45 a,** |
33.91±1.68 a,** |
14.02±0.98 a,** |
290.65±1.86a,** |
293.40±2.42a,** |
| STZ+Ethyl acetate fraction(200 mg/kg) |
36.53±1.51 b,** |
3.12±0.12 b,** |
0.81±0.12b,** |
5.94±0.45 b,** |
20.04±1.09 b,** |
6.70±0.46 b,** |
284.81±1.96b,** |
145.42±1.99b,** |
| STZ+Ethyl acetate fraction (400 mg/kg) |
29.50±1.38 b,** |
3.09±0.12 b,** |
0.72±0.05b,** |
6.52±0.35 b,** |
17.40±0.57 b,** |
4.51±0.33 b,** |
283.28±1.16b,** |
124.12±1.13b,** |
| STZ+Glibenclamide(0.5 mg/kg) |
30.25±1.27 b,** |
3.04±0.12 b,** |
0.80±0.24 b,** |
6.61±0.36 b,** |
18.24±0.79 b,** |
6.40±0.22 b,** |
286.50±6.35 b,** |
115±6.11b,** |
|
