Standard therapy (metformin+diet+exercise) N=20 Siliphos- selenium-methonine-alphalipoic acid+ standard therapy Statistical significance P <0.05* Malondiadehide Ng/dl 0.46(.20-.81) 0.51(.40-.75) 0.56 Leptin ng/ml 7.95(4.46-11.57) 6.9(2.02-10.64) 0.31 Adiponectin Mcg/ml 12358.98 (6187.85-20019.46 11516.60 (7795.92-21880.32 0.85 ALT UI 68.5 (48-99.5) 65.5(39.2-96) 0.56 AST UI 48 (29.5-73.25) 49.5 (29.75-66) 0.85 GGT UI 55.5(39-155.5) 75(39.5-144.5) 0.51 Ferritin Ng/ml 139.10(94-184.2) 150.50(93.2-299.2) 0.81 Glucose mg/dl 98(91-104) 95.5(86.5-104) 0.43 Glycosylated hemoglobin % 5.7 (5.2-6.1) 5.4(5.1-5.8) 0.18 Data expressed as medians (MD) and percentiles (P 25-75)

Table 2: Oxidation and inflammation baseline profiles

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