Standard therapy (metformin +diet +exercise) N=20 Siliphos- selenium-methionine- alpha lipoic acid +standard therapy N=20 Statistical  significance P<0.05*          Malondialdehyde (MDA) ng/dl 0.65(.53-.80) 0.41(.34-.68) 0.040 Leptin ng /ml 9.54(4.46-15.13) 5.6(1.79-9.85) 0.034 Adiponectin mcg/ml 10622.20(7319.78-19154.04) 12944.10(9687.56-20501.88) 0.049 Data expressed as medians (MD) and percentiles (P 25-75)

Table 4: Oxidation and inflammation final profiles comparison.

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