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Figure 7a: Histopathological examination of Knee joint in different groups. normal control, showed normal structure of bone, score 0 (I, II, III). CIA, showed moderate erosion of articular cartilage, edema, and a massive influx of inflammatory cells into the subsynovial connective tissue, score 2. (IV). CIA+betamethasone, showed no erosion of articular cartilage, no edema and normal synovial membrane, score 1. (V). |