| Metabolite |
Range of values |
Reference |
| Glucose (Glc) |
0.05–0.95 |
[37] |
| Glucose-6-phosphate (G6P) |
0.0153–0.90 (a) |
[20] |
| Fructose-6-phosphate (F6P) |
0.0765–1.131 (a) |
[20] |
| GSH |
0.4–2.3 |
[37] |
| Lactic acid (Lac) |
5.02–10.7 |
[29-32,37] |
| Succinate (Succ) |
0.9–3.2 (b) |
[37] |
| pH (cytosol) |
7.1 |
[33] |
| pH (mitochondria) |
<7.6; >7.1 |
|
(a) The concentration of G6P and F6P were originally expressed in µmol/108
cells. To convert these values to mM, we evaluated the cellular volume assuming
spherical cells of typical diameter 50 µm.
(b) The original values refer to the concentration of succinate with respect to the
total cell volume. To convert those values to mitochondrial oncentrations, we
multiply them by a factor of 10. |
