| Author |
Year |
Vaccine |
No. of subjects |
Study outcome |
| Weber et al. [96] |
1985 |
Hepatitis B vaccine |
194 |
Redced HBsAg specific IgG response |
| Roome et al. [141] |
1993 |
Hepatitis B vaccine |
528 |
Reduced anti HBs with extreme obesity |
| Wood et al. [142] |
1993 |
Hepatitis B vaccine |
595 |
Lack of anti HBs associated with obesity |
| Simo Minana et al. [97] |
1996 |
Hepatitis B vaccine |
427 |
Post vaccination anti HBs were low |
| Averhoff et al. [143] |
1998 |
Hepatitis B vaccine |
2,213 |
Decreased immunogenicity was associated with obesity |
| Young et al. [98] |
2001 |
Hepatitis B vaccine |
303 |
Reduced response to HBV |
| Elikiam et al. [99] |
2006 |
Tetanus |
30 |
Anti-tetanus IgG antibodies were low; IL-6 was significantly higher and no change in TNF-a, IL-1b and IL-1ra cytokine levels. |
| Sheridan et al. [102] |
2011 |
Influenza vaccine |
499 |
Decreased 12 months post vaccination IgG production;
Reduced CD69, IFNg and granzyme B in CD8+ T cells. |
| Talbot et al. [103] |
2012 |
Influenza vaccine |
415 |
No consistent relationship between antibody response and obesity |
