Body weight (g)  
Groups Before starvation After starvation change in body weight (g)
Obese      
Starvation-leptin 436.4 ± 8.7a 414.0 ± 15.4b -22.4 ± 4.63*
Starvation-PBS 433.3 ± 8.0a  410.4 ± 12.1b -22.9 ± 3.54*
Free feeding 441.8 ± 16.8a 442.5 ± 19.5a 0.7 ± 0.0
Lean      
Starvation-leptin 233.8 ± 7.4a 216.8 ± 4.8b -17.0 ± 3.45*
Starvation-PBS 233.8 ± 5.2a 217.3 ± 4.8b -16.5 ± 1.58*
Free feeding 224.0 ± 6.6a 224.5 ± 6.9a  0.5 ± 0.0
Values are mean ± S.E; n=8. a, b indicate changes in the body weight before and after starvation (by students T-test). Means that do not share common letter is significantly different at 0.05 level respectively. * indicates comparison between starved PBS or leptin treated vs. free fed in obese or lean groups. *P=.05 by oneway ANOVA
Table 2: Changes in body weight with starvation in WNIN/Ob.
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