Cook et al. Arch Pediatr Adolesc Med, 2003; 157, 821-7 [46] de Ferranti
et al. Circulation, 2004; 110, 2494-7 [47]
Cruz and Goran J Clin Endocrinol Metab, 2004; 89, 108-13 48] Weiss et al. N Engl J Med, 2004; 350, 2362-74 [49] Ford Diabetes Care, 2005; 28, 878-81 [50]
Presence of three or more criteria
Fasting glucose
≥ 110 mg/dL
Fasting glucose
≥ 110 mg/dL
Glucose intolerance (ADAcriteria) Glucose intolerance (ADAcriteria) Fasting glucose
≥ 110 mg/dL
WC> 90th percentile (specific for age and sex, NHANES III) WC>75th percentile (specific for age and sex, NHANES III) WC>90th percentile (specific for age and sex, NHANES III) BMI - Z Score ≥ 2 (specific for age and sex) WC>90th percentile (specific for sex, NHANES III)
TG ≥ 110 mg/dL (specific for age and sex, NCEP) TG
≥ 100 mg/dL
TG ≥ 90th percentile (specific for age and sex, NHANES III) TG ≤ 95th percentile (specific for age and sex, ethnicity, NCHS) TG ≥ 110 mg/dL (specific for age and sex, NCEP)
HDL
<40 mg/dL (specific for age, NCEP)
HDL
< 50 mg/dL
HDL ≤ 10th percentile (specific for age and sex, NHANES III) HDL ≤ 5th percentile (specific for age and sex, ethnicity, NCHS) HDL
< 40 mg/dL (specific for age, NCEP)
BP ≥ 90th percentile (specific for age, sex and height NHBPEP) [46] BP ≥ 90th percentile (specific for age, sex and height NHBPEP)[46] BP ≥ 90th percentile (specific for age, sex and height NHBPEP) [46] BP ≥ 95th percentile (specific for age, sex and height NHBPEP) [46] BP ≥ 90th percentile (specific for age, sex and height NHBPEP) [46]
WC = waist circumference; NHANES III = Third National Health and Nutrition Examination Survey; TG = triglycerides;
NCEP = US National Cholesterol Education Program; BP = blood pressure; ADA = American Diabetes Association;
BMI = body mass index; NHBPEP = National High Blood Pressure Education Program;
NCHS= National Center for Health Statistics; HDL = high density lipoprotein.
Table 5: Definitions for metabolic syndrome for children and adolescents adapted by various authors.
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