| |
Type 2 diabetes |
IFG/IGT |
NGT |
| Genotype |
n (%) |
OR (95% CI)a |
n (%) |
OR (95% CI)a |
n (%) |
| CYP1A2*1C |
|
|
|
|
|
| GG |
101 (56.7) |
1.00 (referent) |
313 (56.2) |
1.00 (referent) |
862 (57.1) |
| GA |
70 (39.3) |
1.04 (0.75-1.45) |
210 (37.7) |
1.02 (0.83-1.26) |
555 (36.8) |
| AA |
7 ( 3.9) |
0.61 (0.27-1.37) |
34 (6.1) |
0.98 (0.64-1.50) |
92 (6.1) |
| GA + AA |
77 (43.3) |
0.98 (0.71-1.35) |
244 (43.8) |
1.02 (0.83-1.24) |
647 (42.9) |
| CYP1A2*1F |
|
|
|
|
|
| AA |
71 (39.7) |
1.00 (referent) |
253 (45.3) |
1.00 (referent) |
654 (43.3) |
| CA |
81 (45.3) |
1.15 (0.82-1.63) |
242 (43.3) |
0.96 (0.78-1.19) |
661 (43.7) |
| CC |
27 (15.1) |
1.33 (0.82-2.16) |
64 (11.4) |
0.86 (0.62-1.19) |
197 (13.0) |
| CA + CC |
108 (60.3) |
1.19 (0.86-1.65) |
306 (54.7) |
0.94 (0.77-1.15) |
858 (56.7) |
IFG, impaired fasting glycemia; IGT impaired glucose tolerance; NGT, normal glucose tolerance; OR, odds ratio; CI, confidence interval.
aAdjusted for age, hospital, rank in the Self-Defense Forces, cigarette smoking, leisure-time physical activity, body mass index, current use of alcoholic beverages (sake,
shochu, beer, whisky and wine), past alcohol use and green tea intake. |
