| Parameters |
Groups |
| Initial |
C |
HF |
HF-R10 |
HF-R20 |
HF-R40 |
| Body mass |
26,9 ± 0,9 |
29,1 ± 0,7 |
27,9 ± 0,6 |
28,4 ± 0,6 |
28,2 ± 0,7 |
| Blood pressure |
125,7 ± 2.6 |
113.0 ± 6.0 |
126.3 ± 1.9 |
118.9 ± 5.4 |
118.0 ± 2.0 |
| Final |
C |
HF |
HF-R10 |
HF-R20 |
HF-R40 |
| Body mass (g) |
29,6 ± 0,9 |
39,2 ± 0,6a |
36,1 ± 0,7a,b |
33,9 ± 0,8a,b |
30,5 ± 0,7b,c,d |
| Blood pressure (mm/Hg) |
119.7 ± 6.9 |
148.0 ± 5.0a |
126.1 ± 3.4 |
107.6 ± 5.5 |
120.0 ± 3.0 |
| Heart mass (g) |
0,070 ± 0,004 |
0,098 ± 0,004a |
0,071 ± 0,003 |
0,076 ± 0,001 |
0,077 ± 0,001 |
| Ventricle mass (g) |
0,054 ± 0,002 |
0,070 ± 0,002a |
0,052 ± 0,002 |
0,055 ± 0,001 |
0,057 ± 0,001 |
| TC (mg/dL) |
103.6 ± 18.1 |
226.2 ± 16.0a |
163.0 ± 16.1b |
128.8 ± 12.3b |
114.6 ± 7.8b |
| Serum TG (mg/dL) |
51.0 ± 4.6 |
87.1 ± 4.8a |
82.0 ± 7.8a |
43.6 ± 8.4b,c |
50.0 ± 2.2b,c |
Abbreviations: CG: Control Group; HF: High-Fat Diet; R10: 10 Mg/Kg/Day of Rosuvastatin; R20: 20 Mg/Kg/Day of Rosuvastatin; R40: 40 Mg/Kg/Day of Rosuvastatin;
TC: Total Cholesterol; TG: Triglyceride. Symbols represent difference with: [a] C group; [b] HF group; [c] HF-R10 group; [d] HF-R20 group. |
