Mechanisms of action Health effect(s)
Anticarcinogenic/Antimutagentic Inhibit cell division, induce apoptosis, block carcinogen activation, enhance DNA repair, induce detoxifying enzymes
Antimicrobial (antifungal, antiviral, antibacterial) Inhibit microbiological growth as antibiotics
Antioxidant Scavenge oxidizing agents, induce SOD, GPX, GST, catalase
Immunomodulatory Increase proinflammatory cytokine release, stimulate natural killer cells
Anti-hypolipidemic Inhibit enzymes in cholesterol and fatty acid synthesis
Anti-hypocholesterolemic Inhibit cholesterol synthesis, enhance cholesterol turnover
Anti-hypertensive Inhibit angiotensin II, induce NO and H2S, cause vasodilation
Anti-diabetic Stimulate insulin production, interfere glucose absorption
Anti-thrombic Reduce trombosane formation, change platelet membrane
Hepatoprotective Increase GSH levels by induction of GST
Table 2: Summary of garlic pharmacological actions and health-promoting benefits [20].
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