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| Figure 5:Expression of LYPD6B mRNA variants in ovarian tissues. (A) Expression levels of the LYPD6B variants in normal ovaries (n=9) and serous ovarian cancers (n=13) using quantitative PCR assays specific for each variant (Roman numerals designate stage of cancer). (B) Mean value of LYPD6B variants expression in normals and cancers. LYPD6B_a was 49 fold over-expressed in serous ovarian cancers compared to normal ovaries (SD; *p<0.001). (C) LYPD6B variant expression levels in several ovarian cancer cell lines. LYPD6B_a and b variants were highly expressed in OVCAR 3 cells. OVCAR 3 (Serous ovarian cancer), TOV21G (clear cell ovarian cancer), ES2 (clear cell ovarian cancer) and NOV-31 (normal ovarian surface epithelium). |
