Affymetrix Id GENE Description R1 Signal2 228360_at LYPD6B LY6/PLAUR domain containing 6B 1.00 941 209436_at SPON1 spondin 1, extracellular matrix protein 0.56 10451 213994_s_at SPON1 spondin 1, extracellular matrix protein 0.54 5044 209437_s_at SPON1 spondin 1, extracellular matrix protein 0.53 2248 213993_at SPON1 spondin 1, extracellular matrix protein 0.53 2206 227763_at LYPD6 LY6/PLAUR domain containing 6 0.53 97 1554863_s_at DOK5 docking protein 5 0.52 469 214844_s_at DOK5 docking protein 5 0.50 1799 227764_at LYPD6 LY6/PLAUR domain containing 6 0.49 293 224488_s_at SPON1 spondin 1, extracellular matrix protein 0.48 231 206414_s_at ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.47 2454 212192_at KCTD12 potassium channel tetramerisation domain containing 12 0.46 6783 212909_at LYPD1 LY6/PLAUR domain containing 1 0.45 2337 35666_at SEMA3F sema domain, immunoglobulin domain, short basic domain, secreted, 3F 0.44 1611 218847_at IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.44 1708 209272_at NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.43 3240 205227_at IL1RAP interleukin 1 receptor accessory protein 0.43 821 204733_at KLK6 kallikrein-related peptidase 6 0.43 1854 219230_at TMEM100 transmembrane protein 100 0.43 601 205593_s_at PDE9A phosphodiesterase 9A 0.42 500 202668_at EFNB2 ephrin-B2 0.42 2312 244523_at MMD monocyte to macrophage differentiation-associated 0.42 182 205473_at ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.42 728 224516_s_at CXXC5 CXXC finger 5 0.41 5420 208025_s_at HMGA2 high mobility group AT-hook 2 0.41 910 232476_at ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH 0.41 497 219836_at ZBED2 zinc finger, BED-type containing 2 0.41 776 239028_at LYPD6 LY6/PLAUR domain containing 6 0.40 119 211596_s_at LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.40 3909 221655_x_at EPS8L1 EPS8-like 1 0.40 887 213386_at C9orf125 chromosome 9 open reading frame 125 0.40 272 226021_at RDH10 retinol dehydrogenase 10 (all-trans) -0.42 695 232579_at LOC 100134229 hypothetical protein LOC100134229 -0.44 260 1Correlation coefficient to LYPD6B; 2Geometric average signal of cancers

Table 6: Transcripts correlated with LYPD6B in data set (3) [21]. Genes correlated to LYPD6B at correlation coefficient > 0.4 or <-.4 in 189 cases.

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