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Figure 4: (a) Histological findings of the loop electrosurgical excision procedure (LEEP) specimen. The tumor was adenosquamous carcinoma. (b) Immunohistochemically, LEEP specimen showed diffuse and strong positivity for p16. (c) In situ hybridization for high-risk human papillomavirus (wide spectrum HPV, DAKO), showing dot-like nuclear positively. (d) Histological feature of the left ovarian tumor. The findings were compatible with mucinous adenocarcinoma. (e) Immunohistochemically, the ovarian tumor showed diffuse and strong positivity for p16. (f) In situ hybridization for high-risk human papillomavirus, showing dot-like nuclear positively. (g) Histological findings of disseminated tumor. The tumor was adenocarcinoma with squamoid feature. (h) Immunohistochemically, disseminated tumor showed diffuse and strong positivity for p16. (i) In situ hybridization for high-risk human papillomavirus, showing dot-like nuclear positively. |