| 
      
        | Alteration of symptoms | Itching(n=37) |  | Vaginal discharge (n=77) |  | Amine odor(n=78) |  |  
        | improved | 30 | 81.10% | 67 | 87.00% | 72 | 92.30% |  
        | unchanged | 7 | 18.90% | 9 | 11.70% | 5 | 6.40% |  
        | worsened | 0 | 0, 0% | 1 | 1.30% | 1 | 1.30% |  
        | pa | <0.001 |  | <0.001 |  | <0.001 |  |  
        | pa: p-value of intra-individual comparison    obtained by exact Wilcoxon test |  |