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Figure 2(E): Virus titer was quantitated using plaque assay
for non-treated (0.1 % DMSO) and emetine treated (0.01 然,
0.1 然, 0.5 然, 1 然, 5 然, 10 然) DENV2-infected Huh-7
cells. DENV2 titer was shown to reduce in dose-dependent
manner for cells post-treated with emetine, correlate with the
IFA images results. DENV2 infection was reduced by more than
2.5 log units in cells treated with emetine at 0.5 然 and 1 然.
At higher concentrations of 5 然 and 10 然 respectively, there
was complete inhibition of DENV2 production. |