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| Figure 3: Inhibition of henipavirus replication by modulators of PKC activity. Vero cells were pretreated for 60 minutes with log dilutions of PKC inhibitor, PMA or 7-octylindolam (50 μM max). Cells were then infected, incubated and assayed as above. Values are expressed as the mean +/- S.E. (n=3). In parallel, cell cytotoxicity assays were performed to determine the relative toxicity of each compound as described in the materials and methods.. |
