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| Figure 2: Chromatograms from gene sequencing of the HIV-1 envelope glycoproteins gp120 and gp41. Partial chromatograms of original wild type strain as well as viral variants selected for in 21 passages in the presence of muparfostat (P21) or in the absence of this drug (C21) showing nucleotide as well as predicted amino acid substitutions (boxed) at positions 152 (A) or 276 (B) in gp120, and at positions 33 (C) and 101 (D) in the gp41. |
