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Figure 1: Decrease of TDR Mutations during the Follow Up in 5 acute/ recent infected patients. The y axis denotes the quantity of each mutation (log copies/mL), which was calculated by multiplying the percentage with viral load. The detection limit of population-based sequencing for drug-resistant HIV-1 is approximately 20%, which is based on general consensus and the cut-off value of the high-throughput sequencing (HTS) we used was 1%. |