Univariate analysis Multivariate analysis
Variable Odds Ratio 95% CI p values Odds Ratio 95% CI p values
Male gender 0.918 0.613-1.375   0.679      
Age ≥40 years 3.405 2.168-5.350 <0.001 2.127 1.233-3.670   0.007
IVDU 0.317 0.190-0.531 <0.001      
Past alcohol abuse 1.277 0.690-2.363   0.436      
BMI >25 kg/m2 1.329 0.859-2.055   0.201      
Genotype 1 or 4 3.606 2.238-5.812 <0.001 3.395 1.900-6.064 <0.001
High viral load 1.180 0.675-2.061   0.562      
Severe inflammation 2.025 0.784-5.233   0.146      
Advanced fibrosis 4.021 2.247-7.197 <0.001 2.926 1.457-5.875   0.003
Hepatic steatosis 2.884 1.842-4.514 <0.001      
Naïve status 0.149 0.077-0.289 <0.001 0.251 0.199-0.528 <0.001
PegIFNα-2a vs.-2b 0.939 0.598-1.473   0.783      
Table 2: Factors associated with treatment failure in the total cohort of HCV patients.
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