| Type |
Gene |
Administration route |
Concentration (μg) |
virus dose |
Mortality (%) |
duration (days) |
Reference |
| |
vp28 |
intramuscular injection |
4 |
2500 SID50 |
13 |
10 |
[108] |
| |
vp28 |
intramuscular injection |
5 |
4x10-8 |
15 |
10 |
[111] |
| |
vp28 |
intramuscular injection |
6 |
1-2 LD50 |
0 |
7 |
[110] |
| |
vp28 |
oral (coated in feed) |
n.d |
n.d |
63% |
15 |
[139] |
| |
vp28 |
oral (chitosan nanoparticles) |
n.d |
n.d |
32% |
15 |
[139] |
| Structural |
vp281 |
intramuscular injection |
6 |
1-2 LD50 |
20 - 47% |
7 |
[110] |
| |
vp26 |
intramuscular injection |
4 |
2500 SID50 |
21% |
10 |
[108] |
| |
vp26 |
intramuscular injection |
25 |
1x10-5 |
100% |
30 |
[140] |
| |
vp24 |
intramuscular injection |
25 |
1x10-5 |
37% |
30 |
[140] |
| |
vp19 |
intramuscular injection |
25 |
1x10-5 |
66% |
30 |
[140] |
| |
vp15 |
intramuscular injection |
25 |
1x10-5 |
37% |
30 |
[140] |
| |
RR2 |
intramuscular injection |
5 |
4x10-8 |
22% |
10 |
[111] |
| Non-structural |
DNA pol |
intramuscular injection |
5 |
4x10-8 |
56% |
10 |
[111] |
| |
PK |
intramuscular injection |
6 |
1-2 LD50 |
7% |
7 |
[110] |
Legends: SID50 - shrimp infctious dose 50% endpoint, LD50 - lethal dose 50% endpoint. N.d. not determined. RR2 - ribonucleotide reductase small subunit. DNA pol - DNA
polymerase. PK - protein kinase. |
