Nominal concentration

Measured concentration                    (ng/mL)

CV (%)

RE (%)a

n

(ng/mL)

MOR     10

10.8

7.2

-7.9

5

40

38.9

1.7

2.8

5

150

153

2.3

-2

5

300

288.8

2.8

3.7

5

600

586.2

3.7

2.3

5

M6G     10

11.4

8.7

-14.2

5

40

43.7

12

-9.3

5

150

152

10

-1.3

5

300

303.3

9.6

-1.1

5

600

629.8

6.4

-5

5

M3G     50

55.8

9.7

-11.6

5

200

177.3

2.4

11.4

5

750

738.2

2.9

1.6

5

1500

1519.9

6.4

-1.3

5

3000

2741.3

5.9

8.6

5

OXY     10

11.6

14.9

-16.1

5

40

45.2

1.7

-13

5

150

150.8

1.5

-0.5

5

300

298.1

0.9

0.6

5

600

576.5

0.5

3.9

5

 

 

 

a RE (%) = [(nominal concentration-mean concentration found)/nominal concentration]×100.
Table 1: Intra-day precision and accuracy for analysis of MOR, M3G, M6G and OXY in human plasma.
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