Glass vials No

NIR Prediction contents using different preprocessing method (%,mg/mg)

Unpreprocessing

VN

FD

FD+VN

SD

SD+VN

1

97.7

91.7

 96.1

92.4

97.0

89.6

2

88.5

92.4

86.7

91.4

84.8

88.1

3

88.4

89.2

88.8

90.8

88.6

88.4

4

93.6

91.3

92.3

91.0

92.4

88.2

5

90.4

91.9

91.1

91.8

91.8

88.9

6

87.2

91.2

87.6

91.4

86.8

87.7

7

93.2

92.4

95.6

91.8

97.7

88.7

8

91.3

91.3

88.7

92.1

88.1

89.1

9

89.5

92.2

87.7

91.9

86.7

89.7

10

98.8

92.7

97.4

90.7

98.6

88.3

11

86.7

94.6

87.3

90.9

87.2

89.0

12

87.3

92.3

87.8

91.2

87.7

89.6

13

85.0

93.1

86.7

92.0

85.6

89.1

14

96.0

92.7

95.9

91.6

95.7

89.3

15

87.5

91.2

89.3

90.8

88.9

89.5

16

87.3

92.7

87.5

90.9

86.4

89.4

17

95.9

91.8

95.8

91.3

96.5

88.8

18

86.1

92.0

88.3

91.1

88.3

89.9

19

84.0

92.3

86.9

93.2

86.5

90.5

20

85.0

93.7

87.9

92.4

87.6

90.2

RMSEP

2.93

2.88

3.29

0.44

4.72

2.03

Table 6: The NIR Prediction results of one batch of cefuroxime sodium in different glass vials by different preprocessing method.
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