Conditions Time (min) Area (10 μg/ml) Degradation (%) Retention time of degradation products
DRO DRO After Degradation
Acidic (HCl) 15 500191.55 415954.95 16.91 3.7, 6.2
Basic (NaOH) 15 409586.98 18.12 3.5
Oxidative 15 42586.89 14.86 3.7
Thermal 15 459827.45 8.1 3.4
Table 1: Forced degradation study of DRO for the proposed method.
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