Adrenergic agonist

SHRNNa SHRHNa

NA

PE

ME

NA

PE

ME

Phase1

Saline

50.1 ± 5.1

48.5 ± 5.4

29.9 ± 5.0

54.2 ± 4.5

61.3 ± 4.6

58.4 ± 4.8

Phase2

CEC
(5µg/Kg)

51.7 ± 5.3

52.3 ± 6.2

47.1 ± 5.6*

62.3 ± 4.7*

64.6 ± 4.7

54.6 ± 4.5

Phase3

CEC (10µg/Kg)

60.4 ± 5.2#

69.4 ± 5.4#

50.7 ± 5.2#

49.3 ± 4.6§

59.3 ± 4.7

64 ± 5.3#

Table 1: Over all mean % change in RCP in response to NA, PE, ME in SHRNNa & SHRHNa rats in absence and presence of low(5g/kg) and high dose of CEC (10g/kg), Values are mean S.E.M *indicate p<0.05 between phase2 and phase1. # indicate p<0.05 between phase 3 and phase 1. indicate p<0.05 between phase 2 and phase 3.
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