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| Figure 6: (A) Lack of interaction of G-CSF with MCP-1 in stimulating migration. MCP-1, but not G-CSF significantly increased migration from control/media alone (p<0.05). Addition of G-CSF to media containing MCP-1 had no effect on migration of THP-1 cells. (B) Pre-incubation with CCR-2 antagonist prevented the increase in migration caused by MCP-1 (20 ng/mL) and addition of G-CSF did not prevent the inhibition of migration. |
