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Figure 1: Cerebral water content in C57/Bl6 mice as a function of age. Experimental data (black squares), unless measured in this study, were obtained from previously published data , i.e., at p5, p10, p15 and p21 [8]. Fitting of data (red line) with a logistic growth model yielded R2=0.98 and allowed direct calculation of remaining water concentrations, which were necessary for metabolite quantification at particular time points if experimentally determined data was unavailable.
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