Table 1 | "ABC" score for ..

		Levels of AD neuropathologic changes
"A"	Thal Phase for Aβ plaques	"B"	Braak and Braak NFT stage	"C"	CERAD score
0	0	0	None	0	None (neg.)
1	1 or 2	1	I or II	1	Sparse (A)
2	3	2	III or IV	2	Moderate (B)
3	4 or 5	3	V or VI	3	Frequent (C)

AD neuropathologic change		B
A	C	0 or 1	2	3
0	0	Not^a	Not^a	Not^a
1	0 or 1	Low	Low	Low^b
1	2 or 3^f	Low	Intermediate	Intermediate^e
2	Any C	Low^c	Intermediate	Intermediate^e
3	0 or 1	Low^c	Intermediate	Intermediate^e
3	2 or 3	Low^c	Intermediate	High

^a High levels of neuritic plaques and low Thal Aβ phase are rare and should prompt reconsideration
^b Widespread NFTs with some Aβ plaques but limited neuritic plaques are infrequent
^c High levels of Aβ or neuritic plaques with low Braak stage should prompt consideration of co-morbidity, eg, CVLs, etc.

Table 1: "ABC" score for AD neuropathological changes. Modified with premission from [100].

Goto home»