Range Median Participants Aß1-42 205-600 500 42 Total Tau 150-540 450 40 Phospho Tau 35-85 61 39 The median values [pg/mL] are representative for all surveys in the last 3 years. The huge range of the cut-off values used in the different laboratories is the source of false positive and false negative evaluations of the sample concentrations analyzed by the individual laboratory.

Table 3: Cut off values [reference ranges] reported by the participating laboratories for their evaluation of analytical data as normal or pathological [example from last survey, Nov 13]

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