Analyte Concentration [pg/ml] Cut-off  related evaluation
    Median Range normal pathol. borderl.
11-Nov Aß 42 748 440-2024 25/30   30-May
Tau 381 99,8-654 13/30 15/30 Feb-30
12-May Aß 42 242 136-393   38/39  
Tau 459 326-650 14/36 25/36  
12-Nov Aß 42 508 69-771 14/40 14/40 Dec-40
Tau 921 315-1292   40/40  
13-May Aß 42 978 693-1311 40/47   Jan-47
Tau 3260 1097-5280   41/48  
13-Nov Aß 42 809 420-1280 33/47 Jan-47 Jan-47
Tau 222 127,5-345 33/47 Jan-47 Jan-47
These interpretations are based on the largely varying cut off values reported by the participants [Table 3]. The data of the five surveys [Mai11-Nov.13] are reported and explained in the commentaries documented in the website of INSTAND (www.instand-ev.de). With the reference to different combinations of the analytes Aß1-42 amyloid peptide and total Tau protein concentrations we summarize the variation of results reported by the individual laboratories according to their individual cut off values [reference range].
Table 4: Evaluations and interpretations of analytical values by the individual laboratories
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