Autoantibodies and isotypes |
GAD65 IgA |
GAD65 IgG |
GAD65 IgM |
TGM3 IgA |
TGM3 IgG |
TGM6 IgA |
TGM6 IgG |
CEREB IgA |
CEREB IgG |
CEREB IgM |
OZ IgA |
0.22 (0.13) |
0.13 (0.39) |
0.28 (0.06) |
0.20 (0.18) |
0.28 (0.05) |
0.29 (0.04) |
0.43 (< 0.01) |
0.40 (< 0.01) |
0.26 (0.08) |
0.22 (0.13) |
OZ IgG |
0.44 (< 0.01) |
0.35 (0.01) |
0.28 (0.05) |
0.31 (0.03) |
0.39 (< 0.01) |
0.43 (< 0.01) |
0.50 (< 0.01) |
0.43 (< 0.01) |
0.27 (0.07) |
0.16 (0.26) |
OZ IgM |
0.01 (0.93) |
-0.16 (0.29) |
0.31 (0.03) |
0.13 (0.39) |
0.15 (0.30) |
0.08 (0.61) |
0.11 (0.45) |
-0.05 (0.76) |
-0.08 (0.58) |
0.28 (0.06) |
Actin IgA |
0.72 (< 0.01) |
0.38 (< 0.01) |
0.48 (< 0.01) |
0.67 (< 0.01) |
0.57 (< 0.01) |
0.76 (< 0.01) |
0.64 (< 0.01) |
0.52 (< 0.01) |
0.01 (0.95) |
0.31 (0.03) |
Actin IgG |
0.43 (< 0.01) |
0.54 (< 0.01) |
0.34 (0.02) |
0.38 (< 0.01) |
0.38 (< 0.01) |
0.42 (< 0.010) |
0.43 (< 0.01) |
0.31 (0.03) |
0.38 (< 0.01) |
0.24 (0.11) |
Actin IgM |
0.40 (< 0.01) |
0.19 (0.20) |
0.76 (< 0.01) |
0.24 (0.10) |
0.25 (0.09) |
0.35 (< 0.01) |
0.34 (0.02) |
0.13 (0.38) |
-0.05 (0.74) |
0.58 (< 0.01) |
|
OZ=Occludin Zonulin, TGM3=Transglutaminase 3, TGM6= Transglutaminase 6, GAD-65=Glutamic Acid Decarboxylase, CEREB=Cerebellar peptide. |
Table 3. Pearson’s correlation coefficients between the neural and cell junction autoantibodies within the group of Mexico City children. The numbers within the parenthesis
are the p-values for testing the significance of the corresponding Pearson’s correlation coefficient. The significant ones are marked in bold. |