Brain Pathologies associated with Cognitive Impairment and Dementia
• Alzheimer’s Disease (β-amyloid plaques, neurofibrillary tangles)
• Cerebrovascular disease
• α-synucleinopathies (Lewy body disease)
• non-Alzheimer tauopathies (Supranuclear palsy, Pick’s disease)
• TDP-43 proteinopathies (Fronto-temporal lobe degeneration)
• Parkinson’s Disease
• HIV Immunodeficiency disease
• Prion Disease (Creutzfeldt-Jakob Disease)
Table 1: Causes of ageing-related cognitive impairment and dementia.
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