Organs andtissues Histological signs   Exposed Concentrations (mgL-1)     A B C D     0 26 39 59 Brain Marked  Congestion  of  cerebrum and cerebellum cells - - ++ ++ Gill Scattered gill filaments and Vascular congestion and thickening of gill filaments - ½ ++ ++ Liver Marked vascular congestion and moderate diffuse fatty degeneration of hepatocytes - ++ ++ ++ Intestine Thinning walls and shortening of villi structure - - ++ ++ Muscle/flesh Goblets cell hyperplasia, muscle - - - -   Necrosis and calcification - - - - ++: = Present and distinct with morphological changes of histological signs on the organ and tissues. 1/2=Present but less marked (mild) than usual - = No lesion and morphological changes in organ and tissues.

Table 4: Histopathological Changes Observed in the Organs and Tissues of C. gariepinus juveniles exposed to Fresh root-bark cold water extracts of P. zeylanica after 21 days of chronic-sub lethal exposure.

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