Characteristic Completers (n = 38) Non-completers (n = 27) p
Plasma GGT, U/L; mean (SD) (reference range 8-61) 212.95 (452.14) 114.30 (137.74) t = 1.10, 63 df, p = 0.28
Plasma ALT, U/L; mean (SD) (reference range < 41) 34.76 (26.66) 37.07 (30.21) t = - 0.33, 63 df, p = 0.75
Plasma AST, U/L; mean (SD) (reference range < 37) 41.74 (40.54) 39.67 (31.99) t = 0.22, 63 df, p = 0.83
Plasma MCV, f/L; mean (SD) (reference range 80-100) 95.94 (5.20) 94.30 (9.83) t = 0.85, 63 df, p = 0.40
CIWA-AR, mean (SD) 13.58 (9.70) 13.81 (8.54) t = -0.10, 63 df, p = 0.92
SADD, mean (SD) 25.97 (7.15) 27.33 (9.07) t = - 0.67, 63 df, p = 0.50
OCDS, mean (SD) 46.39 (8.67) 46.41 (11.09) t = < -0.01, 63 df, p > 0.99
HDRS, mean (SD) 9.50 (5.79) 9.70 (4.70) t = - 0.15, 63 df, p = 0.88
Biological markers were measured and instruments were applied over two weeks before the beginning of double-blind study. GGT, Gamma-Glutamyl Transferase; ALT: Alanine Aminotransferase; AST: Aspartate Aminotransferase; MCV: Mean Cellular Volume; CIWA-AR: Clinical Institute Withdrawal Assessment; SADD, Short Alcohol Dependence Data; OCDS: Obsessive-Compulsive Drinking Scale; HDRS: Hamilton Depression Rating Scale.
Table 4: Baseline hepatic indices and psychometric measures between completers and non-completers of treatment.
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