Participant Characteristics N = 589 N (%) Severe psychological distress N=202 N (%) No severe psychological distressN=387 N (%) P value Age (≥30 year old) 451 (76.6) 164 (81.2) 287 (74.2) 0.06 Gender (Male) 508 (86.2) 161 (79.7) 347 (89.7) 0.00 Born in Canada 555 (94.2) 192 (95.0) 363 (93.8) 0.54 Homelessness 190 (32.3) 74(36.6) 116 (30.0) 0.10 Living with a partner 82 (13.9) 28(13.9) 54(14.0) 0.98 Completed high school 304 (51.6) 99(49.0) 205 (53.0) 0.36 Unstable source of income 191 (32.5) 58(28.7) 133 (34.4) 0.16 High SDS score (≥4) 344 (58.1) 149 (73.8) 195 (50.4) 0.00 Cocaine binge 144 (24.4) 57(28.2) 87 (22.4) 0.12 Alcohol binge 295 (50.1) 118 (58.4) 177 (45.7) 0.00 Polyuse (more than 2 substances excluding cannabis) 463 (78.6) 167 (82.7) 296 (76.5) 0.08 Polyinjection (more than 2 substances among 378 injectors) 231 (61.1) 123 (61.0) 224 (57.9) 0.78 Opioid substitution treatment 35 (5.9) 14(6.9) 21(5.4) 0.47 Regular cannabis use (≥4 days/week) 241 (41) 115 (56.9) 233 (60.2) 0.44

Table 1: Sociodemographic, drug use and behaviors according to severe psychological distress, as ascertained by a K10 score ≥ 30, among 589 cocaine users recruited between October 2010 and April 2013, in Montreal, Quebec, Canada. P-value by Pearson chi-square test

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