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| Figure 2: Anxiolytic effect of ENT1 deletion in mice. ENT1 null mice of both sexes (n=12-15/sex) spent significantly more time in the center of the open field in comparison to their wild-type littermates (n=12-15/sex) (a). No differences in basal locomotor activity were observed between genotypes (b). Significant decreases in both measures between days indicated that the mice habituated normally to the open field chambers. Bars represent mean ± SEM |
