Treatment Condition Ethanol Peak Level (mg%) Ethanol Elimination(mg%/min)
Ethanol   Low 48  ±   5 -0.70 ± 0.05
Ethanol/Caffeine Low 68  ±  6 -0.92 ± 0.14*
Ethanol   High 235  ±  10 -0.78  ± 0.17
Ethanol/Caffeine High 222 ±  19 -0.68   ± 0.02
Table 1: Peak ethanol levels (mg%) and ethanol elimination rate (mg%/min) in female P rats (n = 5-7/group) following acute i.p. exposure to 1 mg/kg caffeine dissolved in 0.5 g/kg 15% w/v ethanol (low) , or 30 mg/kg caffeine dissolved in 2.0 g/kg 15% w/v ethanol (high), or equivalent doses of15% w/v ethanol alone. *, indicates p < 0.05 vs. ethanol alone group.
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