Marker Week ALCAR group Placebo group P value PGP 24 5.6 (2.6; 8.2) n=20 3.3 (2.4; 6.4) n=17 0.23 48 3.7 (1.2; 6.7) n=18 4.1 (1.9; 9.5) n=19 0.63 CGRP 24 0.0 (0; 1.5) n=20 1.0 (0; 1.4) n=17 0.66 48 0.3  (0; 1.5) n=18 1.1 (0; 3.0) n=19 0.16 VIP 24 1.1  (0; 1.9) n=7 1.4 (0; 2.2) n=7 0.56 48 0.6 (0; 3.0) n=9 3.4 (1.7; 4.5) n=8 0.14

Table 2: Percentages of immunostaining for the main neuronal markers [median for each group; interquartile range IQR]. All percentages are multiplied by 1000.

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