Axis I, n=160 (32%) Incidence
(cases/100 py)
Depression, n=123 (25%) Incidence (cases/100 py) Anxiety, n=20 (4%) Incidence
(cases/100 py)
pre HAART (n=290) 2.42 1.94 0.29
early post HAART (n=77) 4.16 3.39 0.17
late post HAART (n=127) 7.16 4.77 1.39
  HR 95% CI p HR 95% CI p HR 95% CI p
Gender
Male 0.36 (0.16-0.84) 0.018 0.28 (0.11-0.71) 0.007 0.19 (0.02-1.66) 0.135
Female 1     1     1    
Military Rank                  
Civilian 0.99 (0.29-3.32) 0.986 1.01 (0.26-3.94) 0.992 0.73 (0.04-12.82) 0.828
Officer 1     1   1      
Enlisted 1.85 (0.93-3.69) 0.082 2.47 (1.07-5.71) 0.034 0.89 (0.24-3.27) 0.857
Race                  
Black 1     1     1 (0.24-3.27) 0.857
Asian 1.13 (0.27-4.81) 0.867 1.54 (0.36-6.60) 0.564 -    
Caucasian 1.65 (1.15-2.37) 0.006 1.74 (1.18-2.55) 0.005 3.20 (1.09-9.37) 0.034
Hispanic/Latino 2.02 (1.05-3.89) 0.035 1.90 (0.92-3.90) 0.082 5.56 (1.05-29.39) 0.043
Antiretroviral status at censor
None 1     1     1    
Yes 1.89 (1.34-2.68) <0.001 2.35 (1.62-3.41) <0.001 1.63 (0.59-4.51) 0.346
NNRTI backbone 1.31 (0.78-2.22) 0.311 1.63 (0.94-2.82) 0.083 0.38 (0.05-3.04) 0.360
PI backbone 1.98 (1.24-3.14) 0.004 2.44 (1.47-4.03) 0.001 2.41 (0.61-9.54) 0.209
HIV diagnosis period
Prior to 1996 1     1     1    
1996-2000 2.18 (1.28-3.70) 0.004 2.22 (1.28-3.84) 0.004 0.98 (0.11-8.55) 0.989
After 2000 5.02 (2.95-8.55) <0.001 3.91 (2.18-7.00) <0.001 8.73 (1.81-42.01) 0.007

HAART = highly active antiretroviral therapy; NNRTI = non-nucleoside reverse transcriptase inhibitor; PI = protease inhibitor; py = person•years

Table 2: Risk of Axis I diagnosis in HIV-infected persons, by demographics & HIV factors, 2008 – Bethesda, Maryland.
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