Adjustments Community sample CLI         HIV infection      p-values community sample vs
Yes No HIV+ HIV-
    All participants
Sample size n=430 n=25 n=192    
Unadjusted 0.63 ± 0.14 0.75 ± 0.14 0.79 ± 0.14  <0.0001 <0.0001
Age- and sex- 0.66 ± 0.12 0.75 ± 0.13 0.73 ± 0.14 <0.0005 <0.0001
Age-, sex- and other* 0.66 ± 0.15 0.75 ± 0.13 0.73 ± 0.15 <0.0005 =0.0001
           
    HIV negative patients with CLI<60 years old   
Sample size n=430 n=25 n=64    
Unadjusted 0.63 ± 0.14 0.75 ± 0.14 0.79 ± 0.14 <0.0001 <0.0001
Age and sex-adjusted 0.64 ± 0.12 0.73 ± 0.12 0.75 ± 0.12 <0.0005 <0.0001
 Age-, sex- and other* 0.64 ± 0.12 0.72 ± 0.13 0.76 ± 0.15 <0.0005 <0.0001
    Men
Sample size n=152 n=21 n=133    
Unadjusted 0.64 ± 0.16 0.75  ±  0.14 0.79 ± 0.14 <0.005 <0.0001
Age- and sex- 0.68 ± 0.16 0.75  ±  0.13 0.73  ±  0.14 =0.017 <0.005
Age-, sex- and other* 0.68 ± 0.17 0.76  ±  0.15 0.75  ±  0.17 =0.014 <0.05
    Smokers
Sample size n=68 n=19 n=128    
Unadjusted 0.63 ± 0.14 0.76 ± 0.14 0.80 ± 0.14 <0.0005 <0.0001
Age- and sex- 0.66 ± 0.16 0.77 ± 0.14 0.78 ± 0.15 <0.005 <0.0001
Age-, sex- and other* 0.66 ± 0.17 0.77 ± 0.15 0.78 ± 0.16 <0.005 <0.0001
    Black Africans
Sample size n=430 n=23 n=113    
Unadjusted 0.63 ± 0.14 0.75 ± 0.14 0.79 ± 0.14 <0.0001 <0.0001
Age- and sex- 0.66 ± 0.12 0.75 ± 0.12 0.71 ± 0.13 <0.0001 <0.0005
Age-, sex- and other*  0.65 ± 0.12 0.75 ± 0.13 0.72 ± 0.15 <0.0005 <0.0005
*Additional adjustments are for hypertension, diabetes mellitus, smoking (except for analysis conducted in smokers only), triglyceride concentrations and HDL cholesterol concentrations. Probability values were further adjusted for non-independence of family members. No differences were noted in groups with or without HIV infection.
Table 4: Comparisons of unadjusted and multivariate-adjusted carotid intima-media thickness (IMT) values in patients with critical limb ischemia (CLI) with (+) or without (-) a human immunodeficiency virus (HIV) infection and in apparently healthy participants from a community sample.
Goto home»