| |
Overall
(n=1240) |
ART
(n=815) |
No ART
(n=425) |
P-value |
| Age (years) |
39.1 ± 10.1 |
40.5 ± 9.7 |
36.5 ± 10.2 |
<0.001 |
| Gender |
|
|
|
0.4 |
| Male |
628 (50.6) |
420 (51.5) |
208 (48.9) |
|
| Female |
612 (49.4) |
395 (48.5) |
217 (51.1) |
|
| Education (years) |
7.5 ± 4.1 |
7.4 ± 4.1 |
7.7 ± 4.1 |
0.2 |
| Skin color |
|
|
|
0.9 |
| Caucasian |
548 (44.2) |
348 (42.7) |
182 (42.8) |
|
| Non-Caucasian |
692 (55.8) |
467 (57,3) |
243 (57.2) |
|
| Smoking (pack-years) |
|
|
|
0.004 |
| 0 |
422 (34.0) |
272 (33.4) |
150 (35.3) |
|
| 1-19 |
498 (40.2) |
309 (37.9) |
189 (44.5) |
|
| =20 |
320 (25.8) |
234 (28.7) |
86 (20.2) |
|
| Physical activity (min/week) |
|
|
|
0.4 |
| ≥150 |
524 (42.3) |
352 (43.2) |
172 (40.5) |
|
| <150 |
716 (57.7) |
463 (56.8) |
253 (59.5) |
|
| Body mass index (kg/m2) |
|
|
|
0.01 |
| <18.5 |
38 (3.1) |
27 (3.3) |
11 (2.6) |
|
| 18.5-24.9 |
670 (54.0) |
466 (57.2) |
204 (48.0) |
|
| 25.0-29.9 |
380 (30.6) |
232 (28.5) |
148 (34.8) |
|
| ≥30.0 |
152 (12.3) |
90 (11.0) |
62 (14.6) |
|
| Time since diagnosis of HIV infection (years) |
|
|
|
<0.001 |
| <3 |
485 (39.1) |
211 (25.9) |
274 (64.5) |
|
| 3-5 |
350 (28.2) |
256 (31.4) |
94 (22.1) |
|
| ≥6 |
405 (32.7) |
347 (42.6) |
58 (13.4) |
|
| Viral load (copies/mL) |
|
|
|
<0.001 |
| <50 |
713 (58.4) |
321 (39.7) |
392 (95.1) |
|
| ≥50 |
508 (41.6) |
488 (60.3) |
20 (4.9) |
|
| CD4 (cells/mm3) |
|
|
|
<0.001 |
| ≥350 |
751 (61.2) |
451 (55.6) |
300 (72.1) |
|
| 200-349 |
295 (24.0) |
215 (26.5) |
80 (19.2) |
|
| <200 |
181 (14.8) |
145 (17.9) |
36 (8.7) |
|
| Glucose (mg/dL) |
86.8 ± 27.6 |
88.2 ± 29.9 |
84.3 ± 22.3 |
0.02 |
| Triglycerides (mg/dL) |
151.9 ± 107.5 |
167.9 ± 121.1 |
120.6 ± 63.3 |
<0.001 |
| Total cholesterol (mg/dL) |
183.1 ± 43.6 |
187.9 ± 45.7 |
173.7 ± 37.5 |
<0.001 |
| HDL cholesterol (mg/dL) |
51.2 ± 13.8 |
51.9 ± 14.1 |
49.8 ± 13.1 |
0.01 |
| LDL cholesterol (mg/dL) |
103.0 ± 35.8 |
104.4 ± 37.4 |
100.4 ± 32.4 |
0.07 |
| Dyslipidemia* |
|
|
|
|
| Yes |
608 (49.6) |
431 (53.3) |
177 (42.5) |
<0.001 |
| No |
617 (50.4) |
378 (46.7) |
239 (57.5) |
|
| Use of lipid-lowering treatment |
|
|
|
|
| Yes |
29 (2.3) |
26 (3.2) |
3 (0.7) |
0.006 |
| No |
1211 (97.7) |
789 (96.8) |
422 (99.3) |
|
* Dyslipidemia: total cholesterol ≥200 md/dL or HDL cholesterol <40 mg/dL |