Adverse Drug Reactions (ADRs) and their characteristics Grade 0 Grade I –Mild Grade II- Moderate Grade III- Severe Grade IV-Life Threatening
Lipodystrophy:
Fat gain/loss on different parts of body e.g. cheeks, lips, unusual fat redistribution.
Skin Hypersensitivity:
Skin rashes, Skin colour changes, Itchiness.
CNS ADRs:
Hallucinations, Headaches, Insomnia.
Peripheral Neuropathy:
Numbness, tinginess, pain at ends e.g. fingers.
No reporting of ADR’s Symptoms causing no or minimal interference with usual social & functional activities. Symptoms causing greater than minimal interference with usual social & functional activities. Symptoms causing inability to perform usual social and functional activities. Symptoms causing
inability to perform basic
self-care functions OR
Medical or operative intervention indicated to prevent permanent impairment, persistent disability or death.
Table 1: Summarised characteristics and classification of ADRs in patients on ARV’s and/or TB drugs.
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