Adverse Drug Reactions (ADRs) and their characteristics Grade 0 Grade I –Mild Grade II- Moderate Grade III- Severe Grade IV-Life Threatening Lipodystrophy: Fat gain/loss on different parts of body e.g. cheeks, lips, unusual fat redistribution. Skin Hypersensitivity: Skin rashes, Skin colour changes, Itchiness. CNS ADRs: Hallucinations, Headaches, Insomnia. Peripheral Neuropathy: Numbness, tinginess, pain at ends e.g. fingers. No reporting of ADR’s Symptoms causing no or minimal interference with usual social & functional activities. Symptoms causing greater than minimal interference with usual social & functional activities. Symptoms causing inability to perform usual social and functional activities. Symptoms causing inability to perform basic self-care functions OR Medical or operative intervention indicated to prevent permanent impairment, persistent disability or death.

Table 1: Summarised characteristics and classification of ADRs in patients on ARV’s and/or TB drugs.

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