| Characteristics |
Any OI recurred |
Total (%) |
Log rank test
p-value |
CHR [95%CI] |
p-value
for CHR |
| Yes (%) |
No (%) |
Marital status
Married
Single
Divorced
Widowed |
172 (42.4)
85 (20.9)
103 (25.4)
46 (11.3) |
60 (46.2)
17 (13.0)
37 (28.5)
16 (12.3) |
232 (43.3)
102 (19.0)
140 (26.1)
62 (11.6) |
0.001 |
1
1.42 (1.09-1.84)
1.11 (0.87-1.41)
1.83 (1.32-2.54) |
0.0088*
0.4236
0.0003* |
Educational status
Not educated
Primary
Secondary
Tertiary |
184 (45.3)
122 (30.1)
71 (17.5)
29 (7.1) |
52 (40.0)
28 (21.5)
24 (18.5)
26 (20.0) |
236 (44.4)
150 (27.6)
95 (17.7)
55 (10.3) |
<0.0001 |
1
0.92 (0.73-1.16)
0.74 (0.56-0.98)
0.45 (0.31-0.68) |
0.461
0.038*
<0.0001* |
Occupational status
Farmer
Merchant
Employed
Daily laborer
House wife
Unemployed
Student |
73 (18.0)
69 (17.0)
69 (17.0)
68 (16.7)
42 (10.3)
70 (17.3)
15 (3.7) |
25 (19.2)
19 (14.6)
38 (29.2)
17 (13.1)
11 (8.5)
18 (13.9)
2 (1.5) |
98 (18.3)
88 (16.4)
107 (20.0)
85 (15.9)
53 (9.9)
88 (16.4)
17 (3.2) |
<0.0001 |
1
0.43 (0.31-0.60)
0.35 (0.25-0.48)
0.86 (0.62-1.21)
0.66 (0.45-0.97)
0.92 (0.66-1.28)
0.58 (0.33-1.01) |
<0.0001*
<0.0001*
0.390
0.034*
0.612
0.055 |
CD4 count (cells/μl) B.
<=100
101-199
200-350
351-499
>=500 |
25 (6.2)
34 (8.4)
80 (19.7)
124 (30.5)
143 (35.2) |
10 (7.7)
14 (10.8)
21 (16.1)
35 (26.9)
50 (38.5) |
35 (6.5)
48 (9.0)
101 (18.8)
159 (29.7)
193 (36.0) |
0.04 |
1
0.45 (0.27-0.77)
0.68 (0.43-1.07)
0.73 (0.48-1.13)
0.57 (0.37-0.87) |
0.003*
0.096
0.158
0.010* |
Hemoglobin (g/dl ) B.
<10
>=10 |
120 (36.4)
210 (63.6) |
14 (21.9)
50 (78.1) |
134 (34.0)
260 (66.0) |
<0.0001 |
1
0.56 (0.45-0.70) |
<0.0001* |
Functional status B.
Working
Ambulatory
Bed ridden |
307 (75.6)
88 (21.7)
11(2.7) |
111 (85.4)
19 (14.6)
- |
418 (78.0)
107 (20.0)
11 (2.0) |
0.044 |
1
1.32 (1.09-1.67)
1.43 (0.72-2.61) |
0.0226*
0.2488 |
Prophylaxis exposure B.
No
Yes |
72 (17.7)
334 (82.3) |
21 (16.2)
109 (83.8) |
93 (17.4)
443 (82.6) |
<0.0001 |
1
0.54 (0.42-0.70) |
<0.0001* |
Prophylaxis Adherence B.
Good
Fair
Poor |
308 (92.2)
11 (3.3)
15 (4.5) |
107 (98.2)
-
2 (1.8) |
415 (93.7)
11 (2.5)
17 (3.8) |
0.001 |
1
1.56 (0.85-2.44)
2.42 (1.43-4.09) |
0.1506
0.001* |
ART B.
No
Yes |
200 (49.3)
206 (50.7) |
68 (52.3)
62 (47.7) |
268 (50.0)
268 (50.0) |
<0.0001 |
1
0.68 (0.56-0.83) |
<0.0001* |
ART regimens ¥ B.
D4T+3TC+NVP
D4T+3TC+EFV
AZT+3TC+NVP
AZT+3TC+EFV
TDF+3TC+EFV
TDF+3TC+NVP |
55 (26.7)
19 (9.3)
60 (29.1)
11 (5.3)
61 (29.6)
- |
7 (11.3)
2 (3.2)
6 (9.7)
1 (1.6)
41 (66.1)
5 (8.1) |
62 (23.1)
21 (7.8)
66 (24.6)
12 (4.6)
101 (37.7)
6 (2.2) |
0.088 |
1
1.00 (0.59-1.69)
1.20 (0.83-1.74)
1.89 (0.98-3.64)
1.58 (1.08-2.32)
0.01 (0.001-1.10) |
0.9999
0.3311
0.0566
0.0197*
0.9881 |
ART adherence B.
Good
Fair
Poor |
194 (94.2)
5 (2.4)
7 (3.4) |
61 (98.4)
1 (1.6)
- |
255 (95.2)
6 (2.2)
7 (2.6) |
<0.0001 |
1
2.15 (0.88-5.25)
3.89 (1.81-8.36) |
0.092
<0.0001* |
Body mass index (kg/m2)F.
<=18.4
18.5-22.9
>=23 |
151 (37.2)
196 (48.3)
59 (14.5) |
38 (29.2)
64 (49.3)
28 (21.5) |
189 (35.3)
260 (48.5)
87 (16.2) |
0.008 |
1
0.87 (0.71-1.08)
0.62 (0.46-0.84) |
0.2142
0.0022* |
CD4 count (cells/μl)F.
<=100
101-199
200-350
351-499
>=500 |
13 (4.8)
31 (11.4)
93 (34.3)
75 (27.7)
59 (21.8) |
5 (5.7)
7 (8.0)
33 (37.9)
26 (29.9)
16 (18.5) |
18 (5.0)
38 (10.7)
126 (35.2)
101 (28.2)
75 (20.9) |
0.55 |
1
0.58 (0.30-1.12)
0.53 (0.29-0.94)
0.46 (0.25-0.83)
0.43 (0.23-0.79) |
0.104
0.031*
0.010*
0.006* |
Functional status F.
Working
Ambulatory
Bed ridden |
345 (85.0)
51 (12.5)
10 (2.5) |
126 (96.9)
3 (2.3)
1 (0.8) |
471 (87.9)
54 (10.1)
11 (2.0) |
0.006 |
1
1.59 (1.18-2.13)
1.32 (0.70-2.47) |
0.0021*
0.3909 |
Prophylaxis exposure F.
No
Yes |
63 (15.5)
343 (84.5) |
20 (15.4)
110 (84.6) |
83 (15.5)
453 (84.5) |
0.003 |
1
0.67 (0.51-0.87) |
0.0032* |
Prophylaxis Adherence F.
Good
Fair
Poor |
316 (92.1)
10 (2.9)
17 (5.0) |
108 (98.2)
1 (0.9)
1 (0.9) |
424 (93.6)
11 (2.4)
18 (4) |
<0.0001 |
1
1.49 (0.79-2.79)
3.48 (2.12-5.71) |
0.217
<0.0001* |
ART F.
No
Yes |
200 (49.3)
206 (50.7) |
68 (52.3)
62 (47.7) |
268 (50)
268 (50) |
<0.0001 |
1
0.68 (0.56-0.83) |
<0.0001* |
