Variable Non-decliners (n=43) Mean (SD) Decliners (n=12) Mean (SD) p value
  Age 56.8 (7.69) 60.8 (9.84) 0.21
  Nadir CD4 (cp/mL) (median) 190 305 0.07
  Current CD4(cp/mL) (median) 525 621 0.23
  HIV duration 18.8 (7.46) 19.6 (6.71) 0.74
  AIDS-defining illness 34.9% 41.7% 0.67
  AIDS (1993 CDC definition) 72.1% 58.3% 0.36
  HAND (% and count) 41.9% (18/43) 75.0% (9/12) 0.01
  HAND categories (count) 13 ANI 3 ANI <0.03
4 MND 3 MND  
1 HAD 3 HAD  
HDS Baseline HDS total score 14.2 (3.94) 13.5 (3.39) 0.55
HDS attention 3.79 (0.71) 3.75 (0.62) 0.85
HDS timed alphabet 5.33 (1.57) 4.33 (2.19) 0.16
HDS memory recall 3.33 (0.77) 3.79 (0.58) <0.04
HDS cube copy 1.81 (0.66) 1.67 (0.65) 0.50
  HDS impaired 23.3% 33.3% 0.48
Table 3: Demographic and cognitive factors stratified by HDS change status.
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