| |
Binding pocket # |
LTNP |
Fast progressor |
Odds Ratio (OR) |
LTNP vs. Fast progressor |
LTNP vs. Fast progressor |
| HLA-A |
|
N |
N |
Uncorrected p value |
Bonferroni’s corrected p value |
| 62Q |
B |
18 (69.23%) |
8 (34.78%) |
4.2187 |
0.0336 |
0.2881 |
| HLA-B |
|
|
|
|
|
|
| 11S |
F* |
2 (7.69%) |
8 (34.78%) |
0.1562 |
0.0463 |
0.0463 |
| 24A |
B |
21 (80.77%) |
11 (47.83%) |
4.5818 |
0.0343 |
0.1344 |
| 24S |
B |
4 (15.38%) |
13 (56.52%) |
0.1398 |
0.0066 |
0.0546 |
| 45E |
B |
4 (15.38%) |
13 (56.52%) |
0.1398 |
0.0066 |
0.1165 |
| 45T |
B |
20 (76.92%) |
8 (34.78%) |
6.25 |
0.0072 |
0.2921 |
| 62G |
A and B |
10 (38.46%) |
2 (8.7%) |
6.5625 |
0.0370 |
0.351 |
| 65R |
A and B |
11 (42.31%) |
2 (8.7%) |
7.7 |
0.0195 |
0.6277 |
| 66N |
B |
11 (42.31%) |
2 (8.7%) |
7.7 |
0.0195 |
0.0195 |
| 67M |
B |
11 (42.31%) |
2 (8.7%) |
7.7 |
0.0195 |
0.2429 |
| 70S |
B |
11 (42.31%) |
2 (8.7%) |
7.7 |
0.0195 |
0.1775 |
| 74D |
F |
4 (15.38%) |
12 (52.17%) |
0.1667 |
0.0149 |
0.0149 |
| 77N |
F |
22 (84.61%) |
11 (47.83%) |
6 |
0.0149 |
0.085 |
| 80I |
F |
21 (80.77%) |
8 (34.78%) |
7.875 |
0.0029 |
0.0353 |
| 81A |
F |
22 (84.61%) |
11 (47.83%) |
6 |
0.0149 |
0.0149 |
| 82L |
External§ |
23 (88.46%) |
11 (47.83%) |
8.3636 |
0.0056 |
0.0056 |
| 83R |
External§ |
23 (88.46%) |
11 (47.83%) |
8.3636 |
0.0056 |
0.0056 |
| 94T |
F |
13 (50%) |
22 (91.3%) |
0.0454 |
0.0013 |
0.0013 |
| 95L |
F |
6 (23.08%) |
13 (56.52%) |
0.2307 |
0.0354 |
0.2244 |
| 97S |
F |
5 (19.23%) |
14 (60.87%) |
0.153 |
0.0071 |
0.1783 |
| HLA-DR |
|
|
|
|
|
|
| 26Y |
4 |
2 (7.69%) |
8 (34.78%) |
2.380952381 |
0.0463 |
0.912684596 |
| 73A |
4 |
26 (100%) |
18 (78.26%) |
N.A. |
0.0417 |
0.0417 |
| 73G |
4 |
9 (34.62%) |
16 (69.56%) |
0.231617647 |
0.0311 |
0.0311 |
| 74R |
4 |
2 (7.69%) |
8 (34.78%) |
0.15625 |
0.0463 |
0.372758417 |
| 77N |
4 |
2 (7.69%) |
8 (34.78%) |
0.15625 |
0.0463 |
0.158747122 |
| 77T |
4 |
26 (100%) |
18 (78.26%) |
N.A. |
0.0417 |
0.149950893 |
|
