| |
|
Atazanavir/Ritonavir (n=10) |
Darunavir/Ritonavir (n=10) |
| Demographics |
|
|
|
| Male, n (%) |
|
4 (40) |
6 (60) |
| Mean age, years (SE) |
|
33 (4.6) |
44 (5.7) |
| No previous smoking, n (%) |
|
2 (20) |
1 (10) |
| Family history, n (%) |
cardiovascular disease |
3 (30) |
4 (40) |
| |
hypercholesterolaemia |
1 (10) |
1 (10) |
| Clinical measures |
|
|
|
| Mean blood pressure, mmHg (SE) |
systolic |
109 (3) |
114 (4) |
| |
diastolic |
69 (2) |
72 (3) |
| Heart rate, beats/minute (SE) |
|
70 (3) |
69 (3) |
| Height, m (SE) |
|
1.71 (2.5) |
1.78 (2.2) |
| Body mass index, kg/m2 (SE) |
|
23 (0.5) |
24 (1.1) |
| Fasting blood analytes |
|
|
|
| Triglycerides, mmol/L (SE) |
|
0.7 (0.1) |
1.0 (0.2) |
| Total cholesterol, mmol/L (SE) |
|
4.3 (0.2) |
4.4 (0.3) |
| HDL cholesterol, mmol/L (SE) |
|
1.4 (0.1) |
1.2 (0.1) |
| LDL cholesterol, mmol/L (SE) |
|
2.7 (0.2) |
2.7 (0.3) |
| Total:HDL cholesterol (SE) |
|
3.2 (0.2) |
3.8 (0.4) |
| Bilirubin, µmol/L (SE) |
|
10 (0.8) |
9 (1.3) |
| Glucose, mmol/L (SE) |
|
4.5 (0.1) |
5.0 (0.3) |
| C-reactive protein, mg/L (SE) |
|
1.6 (0.9) |
1.7 (0.8) |
| D-dimer, mg/L (SE) |
|
0.4 (0.2) |
0.3 (0.1) |
SE: standard error of the mean; HDL: high-density lipoprotein; LDL: low-density lipoprotein. |
